OB/GYN News Articles

Pesticide residue on produce may affect fertility


Eating more fruits and vegetables with high-pesticide residue was associated with a lower probability of pregnancy and live birth following infertility treatment for women using assisted reproductive technologies, report researchers.
The JAMA Network Journals reports that eating more fruits and vegetables with high-pesticide residue was associated with a lower probability of pregnancy and live birth following infertility treatment for women using assisted reproductive technologies, report researchers.
Is preconception intake of fruits and vegetables with pesticide residues associated with outcomes of assisted reproductive technologies?

Animal studies suggest ingestion of pesticide mixtures in early pregnancy may be associated with decreased live-born offspring leading to concerns that levels of pesticide residues permitted in food by the U.S. Environmental Protection Agency may still be too high for pregnant women and infants.

325 women who completed a diet questionnaire and subsequently underwent cycles of assisted reproductive technologies as part of the Environment and Reproductive Health (EARTH) study at a fertility center at a teaching hospital in Boston between 2007 and 2016 by Jorge E. Chavarro, M.D., Sc.D., of the Harvard T. H. Chan School of Public Health, Boston, and colleagues.

Researchers categorized fruits and vegetables as having high or low pesticide residues using a method based on surveillance data from the U.S. Department of Agriculture. They counted the number of confirmed pregnancies and live births per cycle of fertility treatment.

This is an observational study. In observational studies, researchers observe exposures and outcomes for patients as they occur naturally in clinical care or real life. Because researchers are not intervening for purposes of the study they cannot control natural differences that could explain study findings so they cannot prove a cause-and-effect relationship.

Results of the study indicate that eating more high-pesticide residue fruits and vegetables (for example, strawberries and raw spinach) was associated with a lower probability of pregnancy and live birth following infertility treatment. Eating more low-pesticide residue fruits and vegetables was not associated with worse pregnancy and live birth outcomes.

Limitations of the study include that the study estimated exposure to pesticides based on women’s self-reported intake combined with pesticide residue surveillance data rather than through direct measurement. The study also cannot link specific pesticides to adverse effects.

“In conclusion, intake of high-residue FVs [fruits and vegetables] was associated with lower probabilities of clinical pregnancy and live birth among women undergoing infertility treatment. Our findings are consistent with animal studies showing that low-dose pesticide ingestion may exert an adverse impact on sustaining pregnancy. Because, to our knowledge, this is the first report of this relationship to humans, confirmation of these findings is warranted.”


Story Source:Materials provided by The JAMA Network Journals. Note: Content may be edited for style and length.


Journal Reference:

  1. Yu-Han Chiu, Paige L. Williams, Matthew W. Gillman, Audrey J. Gaskins, Lidia Mínguez-Alarcón, Irene Souter, Thomas L. Toth, Jennifer B. Ford, Russ Hauser, Jorge E. Chavarro. Association Between Pesticide Residue Intake From Consumption of Fruits and Vegetables and Pregnancy Outcomes Among Women Undergoing Infertility Treatment With Assisted Reproductive Technology. JAMA Internal Medicine, 2017; DOI: 10.1001/jamainternmed.2017.5038

Read this article on sciencedaily.com www.sciencedaily.com/releases/2017/10/171030112401.htm

Dr. Melissa Seeker joins The Women’s OB/GYN Medical Group of Santa Rosa

Dr. Melissa A. Seeker joins the Women’s OB/GYN Medical Group to become part of a unique team of highly skilled healthcare professionals.

Dr. Melissa A. Seeker has joined Santa Rosa’s preeminent Women’s OB/GYN Medical Group. She is an alumnus of Saint Louis University where she graduated as a member of Alpha Sigma Nu with honors prior to receiving her MD at Creighton University School of Medicine. She served as Chief Resident in Obstetrics and Gynecology at the University Of Arizona College Of Medicine – Phoenix, formerly Banner University Medical Center, where she underwent her residency training.

Dr. Seeker holds many awards and honors in her specialty of Obstetrics and Gynecology including the Award for Excellence in Female Pelvic Medicine and Reconstructive Surgery from the University Of Arizona College Of Medicine – Phoenix. During her medical training, she spent six weeks in the Philippines, Malaysia, and Indonesia providing care to over 3,500 patients with a small medical team. Her resident research project in minimally invasive surgery was selected for presentation at the Society for Gynecologic Surgeons Annual Scientific Meeting. Dr. Seeker also received advanced certification in integrative medicine after completing an elective course from The University of Arizona Center for Integrative Medicine.

Dr. Seeker has special interest in pregnancy education and has volunteered her services to worthy organizations and outreaches specializing in gynecologic care. She is happily married and the proud owner of two boxer dogs and one cat. Outside of medicine, she enjoys traveling, scuba diving, camping, hiking, cooking, and enjoying the great outdoors.

“We are delighted to welcome Melissa to our growing practice,” says Dr. Lela Emad M.D. “Dr. Seeker is a talented and caring physician whose expertise will enhance our services to women in very positive ways.”

About the Women’s OB/GYN Medical Group

As recognized leaders in their field the Women’s OB/GYN Medical Group has offered a full range of premier obstetrics and gynecology services and expertise to women in the North Bay area for more than 25 years. The provider team of expert OB/GYN physicians, certified nurse midwives, family nurse practitioners, and medical assistants provides unmatched care to patients in the Santa Rosa region. As women proudly serving women, this unique group understands patient needs and expectations like no other.

Along with Dr. Seeker, the Women’s OB/GYN Medical Group’s staff of physicians includes; Lela Emad, MD, Shazah Khawaja, M.D., Amita Kachru, M.D.,  Susan Logan, M.D. and Tara Bartlett M.D. Together, these doctors share a unique whole-body approach to medicine as they work to discover the underlying causes of a woman’s health problems, rather than simply treating the symptoms. Every one of the health professionals at Women’s OB/GYN is committed to both alleviating short-term ailments and maximizing long-term health.

The Women’s OB/GYN Medical Group strives to better the lives of all women with a holistic approach to women’s health. To learn more about these fine physicians and the many services provided by the Women’s OB/GYN Medical Group visit the website. To schedule an appointment with Dr. Seeker, please call: (707) 579-1102.

How do women stay heart healthy? Go bananas!

Bananas and avocados -- foods that are rich in potassium -- may help protect against pathogenic vascular calcification, also known as hardening of the arteries.

Bananas and avocados — foods that are rich in potassium — may help protect against pathogenic vascular calcification, also known as hardening of the arteries.

University of Alabama at Birmingham researchers have shown, for the first time, that reduced dietary potassium promotes elevated aortic stiffness in a mouse model, as compared with normal-potassium-fed mice. Such arterial stiffness in humans is predictive of heart disease and death from heart disease, and it represents an important health problem for the nation as a whole.

The UAB researchers also found that increased dietary potassium levels lessened vascular calcification and aortic stiffness. Furthermore, they unraveled the molecular mechanism underlying the effects of low or high dietary potassium.

Such knowledge of how vascular smooth muscle cells in the arteries regulate vascular calcification emphasizes the need to consider dietary intake of potassium in the prevention of vascular complications of atherosclerosis. It also provides new targets for potential therapies to prevent or treat atherosclerotic vascular calcification and arterial stiffness.

A UAB team led by Yabing Chen, Ph.D., UAB professor of pathology and a Research Career Scientist at the Birmingham VA Medical Center, explored this mechanism of vascular disease three ways: living mice fed diets that varied in potassium, mouse artery cross-sections studied in culture medium with varying concentrations of potassium, and mouse vascular smooth muscle cells grown in culture medium.

Working from living mice down to molecular events in cells in culture, the UAB researchers determined a causative link between reduced dietary potassium and vascular calcification in atherosclerosis, as well as uncovered the underlying pathogenic mechanisms.

The animal work was carried out in the atherosclerosis-prone mouse model, the apoliprotein E-deficient mice, a standard model that are prone to cardiovascular disease when fed a high-fat diet. Using low, normal or high levels of dietary potassium — 0.3 percent, 0.7 percent and 2.1 percent weight/weight, respectively, the UAB team found that the mice fed a low-potassium diet had a significant increase in vascular calcification. In contrast, the mice fed a high-potassium diet had markedly inhibited vascular calcification. Also, the low-potassium mice had increased stiffness of their aortas, and high-potassium mice had decreased stiffness, as indicated by the arterial stiffness indicator called pulse wave velocity, which is measured by echocardiography in live animals.

The different levels of dietary potassium were mirrored by different blood levels of potassium in the three groups of mice.

When researchers looked at arterial cross-sections in cultures that were exposed to three different concentrations of potassium, based on normal physiological levels of potassium in the blood, they found a direct effect for the potassium on arterial calcification within arterial rings. Arterial rings in low-potassium had markedly enhanced calcification, while high-potassium inhibited aortic calcification.

“The findings have important translational potential,” said Paul Sanders, M.D., professor of nephrology in the UAB Department of Medicine and a co-author, “since they demonstrate the benefit of adequate potassium supplementation on prevention of vascular calcification in atherosclerosis-prone mice, and the adverse effect of low potassium intake.”

Mechanistic details

In cell culture, low potassium levels in the culture media markedly enhanced calcification of vascular smooth muscle cells. Previous research by several labs including Chen’s group has shown that calcification of vascular smooth muscle cells resembles the differentiation of bone cells, which leads to the transformation of smooth muscle cells into bone-like cells.

So the UAB researchers tested the effect of growing vascular smooth muscle cells in low-potassium cell culture. They found that the low-potassium conditions promoted the expression of several gene markers that are hallmarks of bone cells, but decreased the expression of vascular smooth muscle cell markers, suggesting the transformation of the vascular smooth muscle cells into bone-like cells under low-potassium conditions.

Mechanistically, they found that low-potassium elevated intracellular calcium in the vascular smooth muscle cells, via a potassium transport channel called the inward rectifier potassium channel. This was accompanied by activation of several known downstream mediators, including protein kinase C and the calcium-activated cAMP response element-binding protein, or CREB.

In turn, CREB activation increased autophagy — the intracellular degradation system — in the low-potassium cells. Using autophagy inhibitors, the researchers showed that blocking autophagy blocked calcification. Thus, autophagy plays an important role in mediating calcification of vascular smooth muscle cells induced by the low-potassium condition.

The roles of the CREB activation and autophagy signals were then tested in the mouse artery cross-section and living-mouse models, with low, normal or high levels of potassium in the media or diet. Results in both of those systems supported the vital role for potassium to regulate vascular calcification through calcium signaling, CREB and autophagy.

Besides Chen and Sanders, co-authors of the paper, “Dietary potassium regulates vascular calcification and arterial stiffness,” published in JCI Insight, are Yong Sun, Chang Hyun Byon and Youfeng Yang, UAB Department of Pathology; Wayne E. Bradley, Louis J. Dell’Italia and Anupam Agarwal, UAB Department of Medicine; and Hui Wu, UAB Department of Pediatric Dentistry. Sanders, Agarwal and Chen are also members of the Research Department, Veterans Affairs Birmingham Medical Center.


Story Source:

Materials provided by University of Alabama at Birmingham. Note: Content may be edited for style and length.


Journal Reference:

  1. Yong Sun, Chang Hyun Byon, Youfeng Yang, Wayne E. Bradley, Louis J. Dell’Italia, Paul W. Sanders, Anupam Agarwal, Hui Wu, Yabing Chen. Dietary potassium regulates vascular calcification and arterial stiffness. JCI Insight, 2017; 2 (19) DOI: 10.1172/jci.insight.94920

Read this article on ScienceDaily. ScienceDaily, 5 October 2017. www.sciencedaily.com/releases/2017/10/171005102712.htm.

Healthy Lifestyle Choices to Ensure a Lifetime of Breast Health

In this article Dr. Shazah Khawaja MD  of the Women’s OB/GYN Medical Group of Santa Rosa focuses on empowering women for Breast Cancer Awareness month by highlighting breast cancer prevention strategies.

We believe that when a woman understands the facts about breast cancer she becomes empowered to take the necessary steps towards prevention. Breast health.During October’s National Breast Cancer Awareness Campaign, The Women’s OB/GYN Medical Group is focusing on empowerment through knowledge leading to healthy choices. “We believe that when a woman understands the facts about breast cancer she becomes empowered to take the necessary steps towards prevention. By working to detect the disease in its early stages, a woman is able to make lifestyle changes to reduce the odds of developing the disease in the first place,” explains Dr. Shazah Khawaja, MD, Obstetrician & Gynecologist.

Despite decades of pursing an all-out cure and national efforts aimed at education and prevention, breast cancer remains the most common cancer among women in the United States, second only to skin cancer. Today millions of women are surviving the disease, thanks in part to early detection, improvements in treatment and by enacting healthy lifestyle choices.

The First Step in Staying Healthy

Experts agree that the key to not only surviving a breast cancer diagnosis, but to thriving for years afterwards is early detection followed by early treatment. Routine breast exams and general awareness of how to maintain breast health are both important elements in staying healthy. Practitioners at the Women’s OB/GYN Medical Group encourage routine screening including regular self-breast exams, breast checks during annual gynecologic exams, and screening mammography – all approaches that help to detect breast problems early-on.  “I routinely tell my patients that when we have the opportunity to catch and treat breast problems early, we have a better shot of ensuring the treatment will be successful,” says Dr. Khawaja.

Understanding Breast Cancer Risks for Better Outcomes

Although a having a higher risk for developing the disease may be frightening, it is also true that women who have one or more risk factors for developing breast cancer, never actually develop the disease. With increased awareness about the risk associated with certain factors – particularly those that revolve around lifestyle choices that can be changed – women of all risk levels can become empowered to make better choices.

Some risk factors such as age, genetics or race obviously cannot be changed. Other factors including environment, can also be difficult to modify. While some factors influence risk more than others, a person’s risk for developing breast cancer can change naturally due to aging and by making certain changes in habits and daily practices.

According to the American Cancer Society there are several factors that can affect a woman’s breast cancer risks including:

  • Having children after age 30 (shown to increase the risk of breast cancer in some cases).
  • Birth Control (oral and injectable contraceptives stand out in studies as contributors to breast cancer).
  • Alcohol consumption (the more consumed, the higher the risk).
  • Weight (women who carry extra pounds have a higher risk for developing breast cancer, primarily due to the higher insulin levels that accompany obesity).
  • Smoking (evidence suggests a link between smoking and breast cancer risk, particularly in premenopausal women).

Known Factors that Lower Risk:

Researchers continue to pursue the link between diet and breast cancer risk and many studies actually indicate that diet does play a role. More and more studies cast a wary eye towards red meat consumption, and there is an increased risk associated with high-fat diets, which perpetuates weight gain and obesity (a known breast cancer risk factor).

There may be sure way to prevent breast cancer as of yet, but there are things women can do to help lower the risk. A short list of actions includes;

  • Breast Feeding – for women who breast feed for 1.5 to 2 years studies suggest that there may be some benefit in reducing breast cancer risk
  • Physical Activity – a growing body of evidence indicates that a person’s risk of developing almost any cancer, particularly breast cancer is reduced by adopting a daily routine of physical activity. For example, as little as 1.25 hours of moderate physical activity per week may reduce the risk by up to 18 percent according to some studies.
  • Limit dose and duration of hormone therapy – Combination hormone therapy for more than five years is known to increase the risk of breast cancer. If you and your healthcare provider decide that the benefits of short-term hormone therapy outweigh the risks, use the lowest dose possible.

How OB/GYN Providers Can Help

Self-check breast exams are easy to perform in the home and should be conducted monthly in addition to annual breast exams with a physician at Women’s OB/GYN Medical Group. Depending on a patient’s age and individual health, we may recommend a more frequent interval of regular check-ups with a health care provider. And of course, if you suspect a breast health problem contact a provider immediately.

About the Women’s OB/GYN Medical Group

Women’s OB/GYN Medical Group’s staff of physicians include; Lela Emad, MD, Shazah Khawaja, MD, Amita Kachru, MD, and Susan Logan, MD along with two new providers; Tara Bartlett, D.O and Melissa A. Seeker, M.D. Together, these doctors share a unique whole-body approach to medicine as they strive to find the underlying causes of a woman’s health problems, rather than simply treating the symptoms. The expanded team of health professionals including Certified Nurse-Midwifes and Nurse Practitioners is committed to both alleviating short-term ailments and maximizing long-term health. The Women’s OB/GYN Medical Group strives to better the lives of all women with a holistic approach to women’s health. To learn more visit our website or to call for an appointment dial (707) 579-1102.

Women’s OB/GYN Medical Group Welcomes Elisabeth Niess, Certified Nurse Midwife

Elisabeth Niess, CNM Joins Women’s OB/GYN Medical Group

The newest addition to the OB/GYN Medical Groups team of midwives is Elisabeth (Lisa) Niess. She is a certified nurse midwife (CNM) with a Master of Science in Nursing.  Lisa received her nursing degree in Women’s Health from San Francisco University in 2012 and went on to complete her MSN in midwifery from Frontier Nursing University in 2017.

Lisa provides a full range of midwifery services to women and families of Sonoma County.  She is an advocate for women, encouraging shared decision making to empower women to be active participants in their own care.  She is also passionate about supporting women through the process of labor, birth, and the postpartum period.  As a lactation specialist, she loves providing counseling and resources to the nursing mother.

In her free time, Lisa enjoys spending time with her family, knitting, running, hiking, and baking.

About Certified Nurse-Midwives

Certified Nurse-Midwives (CNMs) are specially trained in providing healthcare to pregnant women from conception through labor and delivery. Many women opt to have a CNM serve as their primary healthcare providers during pregnancy. Maximizing the birth experience and the health of newborns and their mothers is our practice’s primary goal for pregnant patients. Achieving this goal requires expert knowledge about the gestation period and birthing process, as well as heightened empathy between providers and their patients.

Women’s OB/GYN Medical Group’s experienced CNMs offer expertise and tender care guidance to women during their childbearing years. Our CNMs understand that delivery preferences are extremely important and personal to expecting mothers, and that they can also be difficult for some women to determine. To ensure that our patients have the best possible experience during their pregnancies, our CNMs are especially attentive to pregnant mothers’ personal philosophies on giving birth and general reproductive health.

To schedule an appointment with Lisa Niess, please call: (707) 579-1102.

The facts about licorice extracts for treating menopausal symptoms

Licorice roots have a flavorful history, having been used in ancient Egyptian teas and in traditional Chinese medicines, all the way to today as a flavoring agent and candy. And some women now take licorice extracts as supplements to treat menopausal symptoms. But scientists caution that licorice could pose a health risk by interacting with medications.
Women take licorice extracts as supplements to treat menopausal symptoms. But scientists caution that licorice could pose a health risk by interacting with medications.Licorice roots have a diverse and flavorful history, having been used in ancient Egyptian times as a tea and in traditional Chinese medicines, all the way to today as a flavoring agent and as an ingredient in some licorice candies. Some women now take licorice extracts as supplements to treat hot flashes and other menopausal symptoms. But scientists caution that the substance could pose a health risk by interacting with medications.

The researchers are presenting their results today at the 254th National Meeting & Exposition of the American Chemical Society (ACS).

“Concerns about the risk of stroke and breast cancer associated with conventional hormone therapy are prompting women to seek alternatives,” Richard B. van Breemen, Ph.D., says. “Some take botanical dietary supplements, such as licorice, to treat menopausal symptoms like hot flashes.”

But just because a substance is sold as a supplement in a health food store doesn’t mean it is completely safe for all people to take. And on its own, even as a candy, licorice can be harmful in some cases. The U.S. Food and Drug Administration recommends that licorice not be eaten in large amounts during one sitting, and warns that excessive consumption can lead to irregular heart rhythm and muscle fatigue.

“Consuming too much licorice can be harmful, but in our lab, we wondered whether the small amounts in dietary supplements might also cause problems by interfering with drug metabolism or transportation,” says van Breemen, who is at the University of Illinois at Chicago. “The liver has enzymes that process medications, and if these enzymes are induced or inhibited, the drugs will either be processed too quickly or too slowly, respectively.” He points out that these changes could pose a significant safety risk to those who take a daily licorice dietary supplement along with other medication.

Van Breemen’s team analyzed how three types of licorice — two North American species, Glycyrrhiza uralensis and G. inflata, and a European species called G. glabra — affected liver enzymes involved in drug metabolism. They found that all three species inhibit several of these enzymes. Only G. uralensis and G. inflataextracts were found to induce some of these enzymes. Therefore, the researchers say that G. uralensis and G. inflata are more likely to interfere with drug metabolism when compared to G. glabra.

Consumers would have a difficult time using this information, however, because most supplements don’t list the species on their labels. But the researchers are using this knowledge to develop their own licorice therapy that would be safe and effective for women experiencing menopausal symptoms, such as hot flashes. They plan to start clinical trials on their G. glabra-based supplements next year.


Story Source:

Materials provided by American Chemical Society. Note: Content may be edited for style and length.


Read this article on Science Daily: American Chemical Society. “Licorice is a hot trend in hot flashes, but could interact with medications.” ScienceDaily. ScienceDaily, 21 August 2017. <www.sciencedaily.com/releases/2017/08/170821085705.htm.

Women’s OB/GYN Medical Group Physicians Recognized as Among “Top Doctors” of 2017 by Sonoma County Magazine

Santa Rosa physicians, Lela Emad, Shazah Khawaja, and Susan Logan of NCMA Women’s OB/GYN Medical Group have been chosen as among the top Obstetrics and Gynecology doctors by Sonoma Magazine’s Top Doctors survey.

Santa Rosa physicians, Lela Emad, Shazah Khawaja, and Susan Logan Top Doctors 2017

Amita Kachru, MD, Susan Logan MD, Lela Emad MD, Shazah Khawaja, MD

Sonoma Magazine’s Top Doctor 2017 survey polled Sonoma County doctors and medical specialists for healthcare practitioners they most often recommend to a loved one. More than 300 professionals are noted in the September issue as “the crème de la crème” in more than 50 categories. Among physician peers Dr. Lela Emad, Dr. Shazah Khawaja and Dr. Susan Logan ranked at the top for most likely to be referred in the category of OB/GYN specialists. “For the second year in a row, we are honored to be included among such an elite group of physicians in Sonoma County,” said Dr. Emad. “Our group is devoted to the work we do for women in this community, and it is nice to be recognized by our peers.”

About the Women’s OB/GYN Medical Group

With a team made up of compassionate, expert doctors, midwives, nurses and medical assistants aimed at providing unmatched care to patients, the Women’s OB/GYN Medical Group offers a full range of obstetrics and gynecology services to women in the North Bay region. “By putting our patients first, our goal has always been to meet the healthcare needs of women in a comfortable environment, close to home,” says Dr. Emad. “This is something we’ve been doing for more than 25 years.”

Services offered include:

  • general gynecological health screenings
  • state-of-the-art diagnostics
  • comprehensive pregnancy and postpartum care
  • full mid-wifery services
  • minimally invasive laparoscopic surgery
  • uro-gynecological procedures
  • incontinence care
  • menopause care
  • laser hair reduction, skin care and Botox Cosmetic

Women’s OB/GYN Medical Group’s staff of physicians include; Lela Emad, MD, Shazah Khawaja, MD, Amita Kachru, MD, and Susan Logan, MD along with two new providers; Tara Bartlett, D.O and Melissa A. Seeker, M.D. Together, these doctors share a unique whole-body approach to medicine as they strive to find the underlying causes of a woman’s health problems, rather than simply treating the symptoms. The team of health professionals including Certified Nurse-Midwifes and Nurse Practitioners is committed to both alleviating short-term ailments and maximizing long-term health. The practice partnered with Northern California Medical Associates (NCMA) in 2014 to strengthen its network of experienced healthcare providers, directly benefitting patient access to healthcare specialists in the area.

“The theme of our care is ‘women proudly serving women’,” explains Dr. Emad. “As women we understand the needs and expectations of our patients, and we strive to provide each patient with the best experience possible.”

The Women’s OB/GYN Medical Group works to better the lives of all women with a holistic approach to women’s health. To learn more about these fine physicians and the many services provided by the Women’s OB/GYN Medical Group visit the website. Call for an appointment at (707) 579-1102.

Annual mammograms at 40 prevents the most cancer deaths

 
When to initiate screening for breast cancer, how often to screen, and how long to screen are questions that continue to spark emotional debates.

 

When to initiate screening for breast cancer, how often to screen, and how long to screen are questions that continue to spark emotional debates.When to initiate screening for breast cancer, how often to screen, and how long to screen are questions that continue to spark emotional debates. A new study compares the number of deaths that might be prevented as a result of three of the most widely discussed recommendations for screening mammography. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings may provide valuable guidance to women and their physicians about choosing a screening regimen.

To uncover insights that might help women make informed choices about mammography screening, researchers led by Elizabeth Kagan Arleo, MD, of Weill Cornell Medicine and New York-Presbyterian, and R. Edward Hendrick, PhD, of the University of Colorado School of Medicine, used computer modeling to estimate the possible effects of three schemes: annual screening starting at age 40 years, annual screening at ages 45 to 54 years and then biennial screening at ages 55 to 79 years, and biennial screening at ages 50 to 74 years.

The investigators estimated how many breast cancer deaths might be prevented with the different screening schemes. The team found that the recommendation of annual screening starting at age 40 would result in the greatest reduction in breast cancer-specific deaths: a nearly 40 percent reduction in deaths due to breast cancer, compared with 23 percent to 31 percent reductions with other recommendations.

“Our findings are important and novel because this is the first time the three most widely discussed recommendations for screening mammography have been compared head to head,” said Dr. Arleo. “Our research would be put to good use if, because of our findings, women chose to start annual screening mammography starting at age 40. Over the long term, this would be significant because fewer women would die from breast cancer.”

The researchers’ modeling also considered risks associated with screening, including callbacks for additional imaging and, in some cases, a needle biopsy, both of which may reveal the absence of breast cancer despite a suspicious mammography finding.

“Our results show the differences in the three current recommendations for screening mammography in terms of benefits and risks. Women and their physicians can use these findings to guide choices of when a woman begins screening mammography and how often she gets screened,” said Dr. Hendrick.

An estimated 252,710 new cases of invasive breast cancer and 63,410 new cases of non-invasive breast cancer are expected to be diagnosed in women in the United States in 2017, with 40,610 US women expected to die from breast cancer in 2017. About 33 million screening mammography exams are performed each year.

In an accompanying editorial, Otis Brawley, MD, of the American Cancer Society, noted that it is ultimately an individual’s value judgment as to how many false positive mammograms and biopsies are too many to save one life. He stressed that it is important to acknowledge the limitations of mammography and to make it a priority to develop a better test. “The ideal test would be easy to administer and accurate in women of all ages, meaning there would be few false positives and few tumors would be missed,” he wrote.


Story Source:

Materials provided by Wiley. Note: Content may be edited for style and length.


Journal Reference:

  1. Elizabeth Kagan Arleo, R. Edward Hendrick, Mark A. Helvie, Edward A. Sickles. Comparison of recommendations for screening mammography using CISNET models. Cancer, 2017; DOI: 10.1002/cncr.30842

View this article on ScienceDaily.com; “Comparison of screening recommendations indicates annual mammography: Starting at age 40 prevents the most cancer deaths.” ScienceDaily. ScienceDaily, 21 August 2017.

 

Dr. Tara Bartlett D.O. joins The Women’s OB/GYN Medical Group

Dr. Tara Bartlett, DO joins the Women’s OB/GYN Medical GroupDr. Tara C. Bartlett, DO joins the Women’s OB/GYN Medical Group to become the newest member of a team of healthcare professionals made up of compassionate, expert doctors, midwives, nurses and medical assistants, all aimed at providing unmatched care to patients. Dr. Tara C. Bartlett, D.O., is a practicing obstetrician and gynecologist.  She graduated from University of California, Los Angeles as a Phi Beta Kappa with High Honors.  She holds a B.S. degree in Biology with a minor in Global Studies.  Dr. Bartlett obtained her medical degree at Western University of Health Sciences College of Osteopathic Medicine in California.  She completed her residency at Genesys Regional Medical Center in Grand Blanc, Michigan.

Dr. Bartlett holds numerous awards and certifications including Da Vinci robotic surgery certification.  She is trained in minimally invasive robotic and laparoscopic surgery, hysteroscopic surgery, myosure device, novasure endometrial ablation, nexplanon insertion, and intrauterine device placement.  She has participated in a number of research projects pertaining to her specialty including HPV genotyping research.

Dr.  Bartlett has a special interest in international medicine and was awarded the Rafi Younoszai International/Cross-Cultural Health Scholarship Award in 2013.  She has participated in medical outreach providing OB/GYN services for areas with minimal healthcare access in Peru, the Dominican Republic, and northern Spain.  “We are thrilled to welcome Dr. Bartlett as the newest physician to join our unique group of women healthcare providers,” says Dr. Lela Emad of the Women’s OB/GYN Medical Group. “We are honored to have her in our practice. With this addition, both staff and patients gain a very talented and caring physician focused on providing quality support and unmatched healthcare to patients.”

About the Women’s OB/GYN Medical Group

With a team made up of compassionate, expert doctors, midwives, nurses and medical assistants aimed at providing unmatched care to patients, the Women’s OB/GYN Medical Group offers a full range of obstetrics and gynecology services to women in the North Bay region.  Services offered include;

  • General gynecological health screenings
  • State-of-the-art diagnostics
  • Comprehensive pregnancy and postpartum care
  • Full midwifery services
  • Minimally invasive laparoscopic surgery
  • Uro-gynecological procedures
  • Incontinence care
  • Menopause care
  • Laser hair reduction, skin care and Botox Cosmetic

Along with Dr. Bartlett, the Women’s OB/GYN Medical Group’s staff of physicians includes; Lela Emad, MD, Shazah Khawaja, MD, Amita Kachru, MD, and Susan Logan, MD. Together, these doctors share a unique whole-body approach to medicine as they strive to find the underlying causes of a woman’s health problems, rather than simply treating the symptoms. Every one of the health professionals at Women’s OB/GYN is committed to both alleviating short-term ailments and maximizing long-term health.

The Women’s OB/GYN Medical Group strives to better the lives of all women with a holistic approach to women’s health. To learn more about these fine physicians and the many services provided by the Women’s OB/GYN Medical Group visit the website. Call for an appointment at (707) 579-1102.

New Study Concludes: Women have more active brains than men

Largest functional brain imaging study to date identifies specific brain differences between women and men, according to a new report in the Journal of Alzheimer’s Disease

 In the largest functional brain imaging study to date, researchers compared 46,034 brain SPECT (single photon emission computed tomography) imaging studies provided by nine clinics, quantifying differences between the brains of men and women.

The study findings explain why women tend to exhibit greater strengths in the areas of empathy, intuition, collaboration, self-control, and concern.
Side view of the brain summarizing blood flow results from tens of thousands of study subjects shows increased blood flow in women compared to men, highlighted in the red colored areas of the brain: the cingulate gyrus and precuneus. Men in this image have higher blood flow in blue colored areas — the cerebellum.
Credit: Journal of Alzheimer’s Disease

The study findings of increased prefrontal cortex blood flow in women compared to men may explain why women tend to exhibit greater strengths in the areas of empathy, intuition, collaboration, self-control, and appropriate concern. The study also found increased blood flow in limbic areas of the brains of women, which may also partially explain why women are more vulnerable to anxiety, depression, insomnia, and eating disorders.

In the largest functional brain imaging study to date, the Amen Clinics (Newport Beach, CA) compared 46,034 brain SPECT (single photon emission computed tomography) imaging studies provided by nine clinics, quantifying differences between the brains of men and women. The study is published in the Journal of Alzheimer’s Disease.

Lead author, psychiatrist Daniel G. Amen, MD, founder of Amen Clinics, Inc., commented, “This is a very important study to help understand gender-based brain differences. The quantifiable differences we identified between men and women are important for understanding gender-based risk for brain disorders such as Alzheimer’s disease. Using functional neuroimaging tools, such as SPECT, are essential to developing precision medicine brain treatments in the future.”

The brains of women in the study were significantly more active in many more areas of the brain than men, especially in the prefrontal cortex, involved with focus and impulse control, and the limbic or emotional areas of the brain, involved with mood and anxiety. The visual and coordination centers of the brain were more active in men. SPECT can measure blood perfusion in the brain. Images acquired from subjects at rest or while performing various cognitive tasks will show different blood flow in specific brain regions.

Subjects included 119 healthy volunteers and 26,683 patients with a variety of psychiatric conditions such as brain trauma, bipolar disorders, mood disorders, schizophrenia/psychotic disorders, and attention deficit hyperactivity disorder (ADHD). A total of 128 brain regions were analyzed for subjects at baseline and while performing a concentration task.

Understanding these differences is important because brain disorders affect men and women differently. Women have significantly higher rates of Alzheimer’s disease, depression, which is itself is a risk factor for Alzheimer’s disease, and anxiety disorders, while men have higher rates of (ADHD), conduct-related problems, and incarceration (by 1,400%).

Editor-in-Chief of the Journal of Alzheimer’s Disease and Dean of the College of Sciences at The University of Texas at San Antonio, Dr. George Perry said, “Precisely defining the physiological and structural basis of gender differences in brain function will illuminate Alzheimer’s disease and understanding our partners.”

Story Source: Materials provided by IOS Press. Note: Content may be edited for style and length.


Journal Reference:

  1. Daniel G. Amen, Manuel Trujillo, David Keator, Derek V. Taylor, Kristen Willeumier, Somayeh Meysami, Cyrus A. Raji. Gender-Based Cerebral Perfusion Differences in 46,034 Functional Neuroimaging Scans. Journal of Alzheimer’s Disease, 2017; 1 DOI: 10.3233/JAD-170432

Read this article on Science Daily: IOS Press. “Women have more active brains than men: Largest functional brain imaging study to date identifies specific brain differences between women and men, according to a new report in the Journal of Alzheimer’s Disease.” ScienceDaily. ScienceDaily, 7 August 2017.


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