OB/GYN News Articles

Body Image Improves After Just 30-minutes of Exercise

Just one 30-minute bout of exercise makes women feel stronger and thinner, according to a new study. And the positive effect lasts well beyond the activity itself, which may be good news for women concerned about their body image.Just one 30-minute bout of exercise makes women feel stronger and thinner, according to a new UBC study. And the positive effect lasts well beyond the activity itself, which may be good news for women concerned about their body image.

“Women, in general, have a tendency to feel negatively about their bodies,” says study senior author Kathleen Martin Ginis, professor in UBC Okanagan’s School of Health and Exercise Sciences. “This is a concern because poor body image can have harmful implications for a woman’s psychological and physical health including increased risk for low self-esteem, depression and for eating disorders. This study indicates exercise can have an immediate positive effect.”

Martin Ginis, along with her graduate student Lauren Salci, compared the body image and physical perceptions of women who completed 30 minutes of moderate aerobic exercise with those who sat and read. Women in the exercise group had significant improvements in their body image compared to those who didn’t exercise. This positive effect lasted at least 20 minutes post-exercise. The research team further established that this effect was not due to a change in the women’s mood, rather it was linked to perceiving themselves as stronger and thinner.

“We all have those days when we don’t feel great about our bodies,” says Martin Ginis. “This study and our previous research shows one way to feel better, is to get going and exercise. The effects can be immediate.”

Martin Ginis sees this study as a gateway to developing maximally effective body image-enhancing exercise interventions.

According to the National Institutes of Health, nearly one half of North American women experience some degree of body image dissatisfaction and this has become more prevalent over the last three decades.

“We think that the feelings of strength and empowerment women achieve post exercise, stimulate an improved internal dialogue,” says Martin Ginis. “This in turn should generate positive thoughts and feelings about their bodies which may replace the all too common negative ones.”

Story Source:

Materials provided by University of British Columbia Okanagan campus. Note: Content may be edited for style and length.

Breastfeeding after a C-section may help manage pain

Breastfeeding after a cesarean section (C-section) may help manage pain, with mothers who breastfed their babies for at least 2 months after the operation three times less likely to experience persistent pain compared to those who breastfed for less than 2 months, according to new research being presented at this year’s Euroanaesthesia Congress in Geneva (3-5 June).

C-sections account for around a quarter of all births in the UK, USA, and Canada. Chronic pain (lasting for more than 3 months) after C-section affects around 1 in 5 mothers. It is widely accepted that breast milk is the most important and appropriate nutrition in early life, and WHO, the UK Department of Health, and US Department of Health and Human Services all recommend exclusive breastfeeding up to 6 months of age. But until now, little has been known about the effect of breastfeeding on a mother’s experience of chronic pain after C-section.

The study, by Dr Carmen Alicia Vargas Berenjeno and colleagues from the Hospital Universitario Nuestra Señora de Valme in Sevilla, Spain, included 185 mothers who underwent a C-section at the hospital between January 2015 and December 2016. Mothers were interviewed about breastfeeding patterns and the level of chronic pain at the surgical site in the first 24 and 72 hours after C-section, and again 4 months later. The researchers also looked at the effect of other variables on chronic pain including surgical technique, pain in the first 24-72 hours, maternal education and occupation, and anxiety during breastfeeding.

Almost all (87%) of the mothers in the study breastfed their babies, with over half (58%) reporting breastfeeding for two months or longer. Findings showed that around 1 in 4 (23%) of the mothers who breastfed for two months or less still experienced chronic pain in the surgical site 4 months post-op compared to just 8% of those who breastfed for 2 months or longer. These differences were notable even after adjusting for the mother’s age. Further analysis showed that mothers with a university education were much less likely to experience persistent pain compared to those who were less well educated. The researchers also found that over half (54%) of mothers who breastfed reported suffering from anxiety.

The authors conclude: “These preliminary results suggest that breastfeeding for more than 2 months protects against chronic post-cesarean pain, with a three-fold increase in the risk of chronic pain if breastfeeding is only maintained for 2 months or less. Our study provides another good reason to encourage women to breastfeed. It’s possible that anxiety during breastfeeding could influence the likelihood of pain at the surgical site 4 months after the operation.”

The authors are currently analyzing additional data from women interviewed between November 2016 to January 2017, which, when combined with data from all the other women, shows that anxiety is associated with chronic post Cesarean pain in a statistically significant way.


Story Source:

Materials provided by ESA (European Society of Anaesthesiology). Note: Content may be edited for style and length.


Read this article on Science Daily: (European Society of Anaesthesiology). “Breastfeeding may protect against chronic pain after Caesarean section.” ScienceDaily. ScienceDaily, 4 June 2017. www.sciencedaily.com/releases/2017/06/170604115807.htm

Sunscreen use now implicated in widespread vitamin D deficiency

Results from a clinical review find nearly 1 billion people worldwide may have deficient or insufficient levels of vitamin D due to chronic disease and inadequate sun exposure related to sunscreen use.

Results from a clinical review published in The Journal of the American Osteopathic Association find nearly 1 billion people worldwide may have deficient or insufficient levels of vitamin D due to chronic disease and inadequate sun exposure related to sunscreen use.

The study also found that 95 percent of African American adults may have vitamin D deficiency or insufficiency. Vitamin D variations among races are attributed to differences in skin pigmentation.

“People are spending less time outside and, when they do go out, they’re typically wearing sunscreen, which essentially nullifies the body’s ability to produce vitamin D,” said Kim Pfotenhauer, DO, assistant professor at Touro University and a researcher on this study. “While we want people to protect themselves against skin cancer, there are healthy, moderate levels of unprotected sun exposure that can be very helpful in boosting vitamin D.”

Dr. Pfotenhauer also said chronic diseases like Type 2 Diabetes and those related to malabsorption, including kidney disease, Crohn’s and celiac disease greatly inhibit the body’s ability to metabolize vitamin D from food sources.

Considered a hormone rather than a vitamin, vitamin D is produced when skin is exposed to sunlight. Vitamin D receptors are found in virtually every cell in the human body. As a result, it plays a wide role in the body’s functions, including cell growth modulation, neuromuscular and immune function and inflammation reduction.

Symptoms for insufficient or deficient vitamin D include muscle weakness and bone fractures. People exhibiting these symptoms or who have chronic diseases known to decrease vitamin D, should have their levels checked and, if found to be low, discuss treatment options. However, universal screening is likely neither necessary nor prudent absent significant symptoms or chronic disease.

Increasing and maintaining healthy vitamin D levels can be as easy as spending 5-30 minutes in midday sun twice per week. The appropriate time depends on a person’s geographic location and skin pigmentation — lighter skin synthesizes more vitamin D than darker skin. It is important to forgo sunscreen during these sessions because SPF 15 or greater decreases vitamin D3 production by 99 percent.

“You don’t need to go sunbathing at the beach to get the benefits,” said Dr. Pfotenhauer. “A simple walk with arms and legs exposed is enough for most people.”

Food sources such as milk, breakfast cereals, and Portobello mushrooms are also fortified with vitamin D. Dr. Pfotenhauer said supplements are a good option, as they are effective and pose few risks, provided they are taken as directed and a physician is consulted beforehand.

Research is ongoing to determine whether vitamin D deficiency has a role in multiple sclerosis, autoimmune disorders, infections, respiratory disease, cardiometabolic disease, cancer, and fracture risk.

“Science has been trying to find a one-to-one correspondence between vitamin D levels and specific diseases,” said Dr. Pfotenhauer. “Given vitamin D’s ubiquitous role in the body, I believe sufficient vitamin D is more about overall health. Our job as osteopathic physicians is to recognize those patients that need to be tested and treat them accordingly.”

Currently, insufficiency is defined as between 21 and 30 ng/ml and deficiency is considered below 20ng/ml by the Endocrine Society.


Story Source: Materials provided by American Osteopathic Association. Note: Content may be edited for style and length.

Read this article on Science Daily: American Osteopathic Association. “Widespread vitamin D deficiency likely due to sunscreen use, increase of chronic diseases, review finds.” ScienceDaily. ScienceDaily, 1 May 2017. www.sciencedaily.com/releases/2017/05/170501102258.htm.

May is the Month for Women – A good time to focus on Women’s Health

In honor of Mother’s Day and National Women’s Health Week Dr. Lela Emad of Women’s OB/GYN Medical Group offers timely insights for staying healthy.

With the goal of empowering women to make health a priority, the U.S. Department of Health and Human Services Office celebrates National Women’s Health Week beginning on May 14th – which is also Mother’s Day. This weeklong event is offered to encourage women to take steps to improve health with a focus on annual screenings, lifestyle choices and prevention.

“It is certainly important for women to be vigilant about testing for conditions that are most successfully treated when caught early, including breast cancer and colon cancer. And, another good way to stay healthy is to have routine check-ups to screen for the basic health concerns,” says Dr. Lela Emad obstetrician & gynecologist. “Heart disease is still the top killer of women in the U.S. therefore it is equally important for women to monitor blood pressure, cholesterol levels and to be aware of any potential for diabetes.”

Life expectancy in the U.S. for women now averages a full eight decades – barring accidents or major health issues. With all that living to look forward to, it’s a good idea to adopt healthy habits as early in life as possible. A look at the trends to better health reveals that there are some very simple ways to optimize health, and make life worth living.

Schedule an Appointment

One important step consists of scheduling a visit to a healthcare provider for a well-woman checkup that includes preventive screenings. Health professionals recommend adolescent girls and women start routine, annual gynecologic visits around the age of 14 unless otherwise indicated by their general practitioners. These important checkups give women an opportunity to discuss both gynecologic and general health concerns. This type of screening can include the following:

  • Blood pressure, Height, Weight
  • Lipid Panel (cholesterol and triglycerides)
  • Breast Cancer Screening
  • Cervical Cancer Screening
  • A hemoglobin test, an indicator for anemic
  • Pap & HPV tests

Exercise – Be more active!

Sitting for prolonged periods at a desk or in front of the computer may be a necessity for many a woman’s livelihood, but it’s not good for the body. Research shows that women who sit for more than six hours a day have a 40 percent higher risk of dying from any cause when compared to women who sit for fewer than three hours—regardless of their fitness levels.

Exercise is hands-down the best thing both men and women can do to improve health. And the best way to get fit and stay fit is to get moving. Exercise increases energy and releases endorphins—which in turn increases a person’s happiness quotient. Several recent studies indicate that staying active is associated with a longer life expectancy.

Exercise doesn’t need to be drudgery, a good way to incorporate a routine that endures the test of time is to choose activities that are fun. Simply going for a 20-minute walk with a friend is extremely beneficial to overall healthfulness. Just 2.5 hours weekly (about 20 minutes a day) of moderate aerobic exercise such as walking provides all the major health benefits a body needs to stay healthy.

Eating for Life

Research proves that eating more fresh vegetables is one of the simplest way to improve overall healthfulness. A vegetable-rich diet can help protect the body from arthritis, heart disease, stroke, dementia and a variety of cancers – and it might also slow down the aging process. In fact, one study found that people who consume at least seven portions of fresh vegetables and fruit each day have as much as 42 percent lower risk of dying from any cause, compared to those who eat one portion or less.

Breast Health

Routine breast exams and general awareness of how to maintain breast health are important elements in maintaining a healthy lifestyle for women. Screening methods such as regular self-breast exams, breast checks during routine gynecologic exams, and screening mammographies can all help to detect breast problems early-on.

For National Women’s Health Week, the office of Women’s Health US Dept. of Health & Human Services also recommends that women pay attention to mental health, get plenty of sleep and take steps every day to manage stress. And, of course avoid unhealthy behaviors, such as smoking, texting while driving, and not wearing a seatbelt or bicycle helmet.

About Women’s OBGYN Medical Group

The provider team of expert OB/GYN physicians, certified nurse midwives, family nurse practitioners, and medical assistants provides unmatched care to patients in our region. As women proudly serving women, we understand the needs and expectations of our patients. For more information call (707) 579-1102 or visit the Women’s OB/GYN website.

Could hot flashes indicate risk of heart disease?

Study shows younger midlife women with hot flashes more likely to have poor vascular function

Hot flashes, one of the most common symptoms of menopause, have already been shown to interfere with a woman’s overall quality of life. A new study shows that, particularly for younger midlife women (age 40-53 years), frequent hot flashes may also signal emerging vascular dysfunction that can lead to heart disease. The study outcomes are published online today in Menopause, the journal of The North American Menopause Society (NAMS).

The study involving 272 nonsmoking women aged 40 to 60 years is the first to test the relationship between physiologically assessed hot flashes and endothelial cell (the inner lining of the blood vessels) function. The effect of hot flashes on the ability of blood vessels to dilate was documented only in the younger fertile of women in the sample. There was no association observed in the older women (age 54-60 years), indicating that early occurring hot flashes may be those most relevant to heart disease risk. The associations were independent of other heart disease risk factors.

Cardiovascular disease is the leading cause of death in women. The results from the study, “Physiologically assessed hot flashes and endothelial function among midlife women,” may offer valuable information for healthcare providers working to assess the risk of heart disease in their menopausal patients. Hot flashes are reported by 70% of women, with approximately one-third of them describing them as frequent or severe. Newer data indicate that hot flashes often start earlier than previously thought — possibly during the late reproductive years — and persist for a decade or more. “Hot flashes are not just a nuisance. They have been linked to cardiovascular, bone, and brain health,” says Dr. JoAnn Pinkerton, executive director of NAMS. “In this study, physiologically measured hot flashes appear linked to cardiovascular changes occurring early during the menopause transition.”

 


 

Story Source:Materials provided by The North American Menopause Society (NAMS). Note: Content may be edited for style and length.

Journal Reference:

Rebecca C. Thurston, Yuefang Chang, Emma Barinas-Mitchell, J. Richard Jennings, Roland von Känel, Doug P. Landsittel, Karen A. Matthews. Physiologically assessed hot flashes and endothelial function among midlife women. Menopause, 2017; 1 DOI: 10.1097/GME.0000000000000857

 

Mother’s folic acid intake during pregnancy may decrease hypertension risk in children

Avocado – rich in folic acid.

A new article published in the American Journal of Hypertension finds that babies born to mothers with cardiometabolic risk factors were less likely to develop high blood pressure if their mothers had higher levels of folate during pregnancy.

Since the late 1980s, the prevalence of childhood elevated blood pressure has increased in the United States, in particular among African Americans. From a life course perspective, childhood high blood pressure can predict higher blood pressure values later in life, and people with higher blood pressure are at greater risk of developing cardiovascular, metabolic and kidney disease and stroke. Research has also shown that maternal cardiometabolic risk factors during pregnancy — including hypertensive disorders, diabetes, and obesity — are associated with higher offspring blood pressure.

Because controlling hypertension and cardiovascular disease in adults is difficult and expensive, identifying early-life factors for the prevention of high blood pressure may be an important and cost effective public health strategy.

There is growing evidence that maternal nutrition during pregnancy, through its impact on the fetal intrauterine environment, may influence offspring cardiometabolic health. Folate, which is involved in nucleic acid synthesis, gene expression, and cellular growth, is particularly important.

In young adults, higher folic acid intake has been associated with a lower incidence of hypertension later in life. Citrus juices and dark green vegetables are good sources of folic acid. However, the role of maternal folate levels, alone or in combination with maternal cardiometabolic risk factors on child blood pressure has not been examined in a prospective birth cohort.

In the current study, researchers analyzed the data from a prospective U.S. urban birth cohort, enriched by low-income racial and ethnic minorities at high risk for elevated BP, to examine whether maternal folic acid levels and cardiometabolic risk factors individually and jointly affect offspring blood pressure.

Researchers included 1290 mother-child pairs, 67.8% of which were Black and 19.2% of which were Hispanic, recruited at birth and followed prospectively up to age 9 years from 2003 to 2014 at the Boston Medical Center. Of the mothers, 38.2% had one or more cardiometabolic risk factors; 14.6% had hypertensive disorders, 11.1% had diabetes, and 25.1% had pre-pregnancy obesity. A total of 28.7% of children had elevated systolic blood pressure at age 3-9 years. Children with higher systolic blood pressure were more likely to have mothers with pre-pregnancy obesity, hypertensive disorders, and diabetes. Children with elevated systolic blood pressure were also more likely to have lower birth weight, lower gestational age, and higher BMI.

The study findings suggest that higher levels of maternal folic acid may help counteract the adverse associations of maternal cardiometabolic risk factors with child systolic blood pressure, although maternal folic acid levels alone were not associated with child systolic blood pressure. Among children born to mothers with any of the cardiometabolic risk factors, those whose mothers had folic acid levels above the median had 40% lower odds of elevated childhood systolic blood pressure. These associations did not differ appreciably in analyses restricted to African Americans, and they were not explained by gestational age, size at birth, child postnatal folate levels or breastfeeding.

“Our study adds further evidence on the early life origins of high blood pressure,” said Dr. Xiaobin Wang, the study’s senior corresponding author. “Our findings raise the possibility that early risk assessment and intervention before conception and during pregnancy may lead to new ways to prevent high blood pressure and its consequences across lifespan and generations.”


Story Source:

Materials provided by Oxford University Press USA. Note: Content may be edited for style and length.


Journal Reference:

  1. Hongjian Wang, Noel T. Mueller, Jianping Li, Ninglin Sun, Yong Huo, Fazheng Ren, Xiaobin Wang. Association of Maternal Plasma Folate and Cardiometabolic Risk Factors in Pregnancy with Elevated Blood Pressure of Offspring in Childhood. American Journal of Hypertension, 2017; DOI: 10.1093/ajh/hpx003

Cite This Page:

Oxford University Press USA. “High folic acid level in pregnancy may decrease high blood pressure in children.” ScienceDaily. ScienceDaily, 8 March 2017. <www.sciencedaily.com/releases/2017/03/170308081047.htm>.

Most Women of Child Bearing Age Lack Knowledge of Healthy Diet Says New Study

Dr. Lela Emad of the Women’s OB/GYN Medical Group discusses the latest findings on diet and nutrition among women and offers some guidelines for women planning for pregnancy.

A new study by the University of Pittsburgh Schools of the Health Sciences uncovers a national trend toward a less than optimal diet among women prior to pregnancy. “This information is particularly concerning for women who intend to conceive,” says Dr. Lela Emad of the Women’s OB/GYN Medical Group of Santa Rosa. “It’s imperative that prior to pregnancy, women follow a higher standard of nutrition for several reasons; to ensure healthy growth of the fetus, to reduce risks associated with premature birth, and to avoid the possibility of preeclampsia and maternal obesity – both of which carry added risks to the mother and baby.”

The study, published in the Journal of the Academy of Nutrition and Dietetics, assessed more than 7,500 women participants using the Healthy Eating Index-2010, measuring quality of diet including the intake for key food groups, while also measuring the consumption of less desirable aspects of a typical American diet such as refined grains, salt and calories from solid fats and sugars from food as well as from alcohol consumption.

Ultimately, more than a third of the calories the women in the study consumed came from ‘empty calories’ from such things as;

  • sugar-sweetened beverages,
  • pasta dishes
  • grain desserts
  • Soda
  • beer, wine and spirits

“This list consists of just about everything we would recommend a woman who was in a preconception phase to avoid,” Dr. Emad points out. “A healthy diet goes a long way toward ensuring a healthy pregnancy, and planning ahead for pregnancy by participating in a Preconception Healthcare Plan is one of the best things a woman can do both for her baby and for herself.”

What is Preconception Healthcare

Preconception healthcare describes medical care provided to a woman that is designed to increase the chances of having a positive pregnancy experience and a healthy baby. Preconception healthcare is uniquely designed for every individual, customized for personal needs and circumstances. It typically offers an introduction to guidelines for a healthy diet as part of the overall education and planning process.

“We encourage parents – that is, both parents – to begin making healthy lifestyle changes up to one full year prior to trying to get pregnant,” explains Dr. Emad. “This process improves a woman’s chances of becoming pregnant and prepares her body so it can provide the best environment for her infant.” During a preconception care visit, the OB/GYN healthcare provider will focus on lifestyle, medical and family history, previous pregnancies and currently prescribed medications. In addition to diet and exercise, topics may include alcohol, tobacco, and caffeine use; recreational drug use, birth control, family histories, genetics as well as health issues and other concerns (diabetes, high blood pressure, depression, obesity, etc.)

Healthy Diet and Supplements

“We also encourage our patients and their families to adopt a nutrient rich and calorie conscious diet prior to and during pregnancy. This is the best way to prevent excessive weight gain and cut the potential risk of obstetric complications,” says Dr. Emad. “Planning ahead and taking steps to ensure optimal pre-pregnancy health is a great way to create a healthy family.”

Learning how to make smart food choices as well as being mindful about food preparation is important, as is knowing which foods to avoid or limit during pregnancy. Foods that contain sources of folic acid (vitamin B9) are important nutritional elements to incorporate into both the preconception and pregnancy diet. Folic acid helps to prevent some birth defects – particularly those affecting the brain and spinal cord. Folic acid is best taken before pregnancy and in the very early stages of pregnancy.

Although the bulk of nutrients should ideally come from eating fresh healthy foods, it is generally recommended that women start taking a prenatal vitamin supplement before pregnancy. Prenatal vitamin supplements are specifically formulated to contain all the recommended daily vitamins and minerals needed before and during pregnancy.

About Women’s OBGYN Medical Group

The Women’s OB/GYN Medical Group strives to better the lives of all women with a holistic approach to women’s health. To learn more about these fine physicians and the many services provided by the Women’s OB/GYN Medical Group visit the website. Call for an appointment at (707) 579-1102.

Good news for mature women: weight loss is possible after menopause

Talk to a woman in menopause and you’re likely to hear complaints about hot flashes and an inability to lose weight, especially belly fat. A new study shows how regular exercise can help reduce weight and control bothersome symptoms such as hot flashes, even in women who previously led sedentary lifestyles. The study outcomes are being published online today in Menopause, the journal of The North American Menopause Society (NAMS).

Decreased estrogen levels during the menopause transition often create an array of physical and mental health issues that detract from a woman’s overall quality of life. The article “Improvements in health-related qualify of life, cardio-metabolic health, and fitness in postmenopausal women after a supervised, multicomponent, adapted exercise program in a suited health promotion intervention: a multigroup study” reports on 234 Spanish postmenopausal women aged 45 to 64 years who had at least 12 months of sedentary behavior and engaged in a supervised 20-week exercise program for the study. After the intervention, the participants experienced positive changes in short- and long-term physical and mental health, including significant improvements in their cardiovascular fitness and flexibility. In addition, they achieved modest but significant reductions in their weight and body mass index, and their hot flashes were effectively managed. This is especially good news for women who are reluctant to use hormones to manage their menopause symptoms and are looking for safe but effective nonpharmacologic options without adverse effects.

“Growing evidence indicates that an active lifestyle with regular exercise enhances health, quality of life, and fitness in postmenopausal women,” says Dr. JoAnn Pinkerton, NAMS executive director. “Documented results have shown fewer hot flashes and improved mood and that, overall, women are feeling better while their health risks decrease.


Story Source:Materials provided by The North American Menopause Society (NAMS). Note: Content may be edited for style and length.


Read this article on ScienceDaily:

The North American Menopause Society (NAMS). “Weight loss actually possible after menopause.” ScienceDaily. ScienceDaily, 15 February 2017. <www.sciencedaily.com/releases/2017/02/170215084052.htm>.

Can eating soy products affect breast health?

Georgetown Lombardi Comprehensive Cancer Center researchers have used animal models to reveal new information about the impact — positive and negative — that soy consumption could have on a common breast cancer treatment.

The scientists have uncovered the biological pathways in rats by which longtime soy consumption improves effectiveness of tamoxifen and reduces breast cancer recurrence. But they also show why eating or drinking soy-based foods for the first time while being treated with tamoxifen can, conversely, reduce effectiveness of the drug, and promote recurrence.

The study, published in Clinical Cancer Research, uncovers the molecular biology behind how soy consumption, especially its most active isoflavone, genistein, affects tamoxifen — both positively and negatively.

It also mirrors what has been observed in breast cancer patients, says the study’s senior investigator Leena Hilakivi-Clarke, PhD, professor of oncology at Georgetown Lombardi.

“There has long been a paradox concerning genistein, which has the similar structure as estrogen and activates both human estrogen receptors to a degree. Estrogen drives most breast cancer growth, yet high soy intake among women in Asian countries has been linked to a breast cancer rate that is five times lower than Western women, who eat much less soy,” she says. “So why is soy, which mimics estrogen, protective in Asian women?”

More than 70 percent of the 1.67 million women diagnosed with breast cancer worldwide in 2012 was estrogen-receptor positive, and tamoxifen and other endocrine therapies meant to reduce the ability of estrogen to promote cancer growth, are the most common drugs used for these cancers. Although endocrine therapies can be highly effective in preventing or treating breast cancer, about half of patients who use them exhibit resistance and/or have cancer recurrence.

Employing a more advanced rat model of breast cancer and tamoxifen use than has been used in past studies, the researchers found that the timing of genistein intake is the central issue.

Longtime sustained use of genistein before development of breast cancer improves overall immunity against cancer, thus protecting against cancer development and recurrence, says the study’s lead researcher, Xiyuan Zhang, PhD.

“It also inhibits a mechanism called autophagy that would allow cancer cells to survive, which explains why it helps tamoxifen work,” says Zhang, a member of Hilakivi-Clarke’s laboratory when this study was conducted. She is currently a postdoctoral researcher at the National Institutes of Health.

Previous studies in women show no evidence of adverse effects of soy intake on breast cancer outcome, the researchers say, adding that research has also shown that Asian and Caucasian women who consumed as little as 1/3rd cup of soymilk daily (10 mg. of isoflavones) had the lowest risk of breast cancer recurrence.

The animal studies suggest it is a different story when soy consumption begins after breast cancer develops.

Starting consuming genistein in a diet after breast cancer develops in the animals did not trigger anti-tumor immune response to eliminate cancer cells, Zhang says. “We do not know yet why this made the animals resistant to the beneficial effects of tamoxifen and increased risk of cancer recurrence,” she continued.

Animals consuming genistein as adults on had a 7 percent chance of breast cancer recurrence after tamoxifen treatment, compared with a 33 percent recurrence with rats exposed to genistein only after breast cancer developed.

“We have solved the puzzle of genistein and breast cancer in our rat model, which perfectly explains the paradox seen in earlier animal studies and patients,” says Hilakivi-Clarke. “While many oncologists advise their patients not to take isoflavone supplements or consume soy foods, our findings suggest a more nuanced message — if these results hold true for women. Our results suggest that breast cancer patients should continue consuming soy foods after diagnosis, but not to start them if they have not consumed genistein previously.”


Story Source:

Materials provided by Georgetown University Medical Center. Note: Content may be edited for style and length.


Read this article on ScienceDaily: Georgetown University Medical Center. “Understanding when eating soy might help or harm in breast cancer treatment.” ScienceDaily. ScienceDaily, 1 February 2017. www.sciencedaily.com/releases/2017/02/170201092711.htm.

Women’s OB/GYN Medical Group of Santa Rosa Focuses on Cervical Health Awareness Month

Dr. Lela Emad offers hope for women concerned about cervical cancer risks, and shares important tips for staying healthy.

Healthy Women January is Cervical Health Awareness Month and there’s good news for the 13,000 women in the United States who are expected to be diagnosed with cervical cancer this year; early detection increases the 5-year survival rate for women with invasive cervical cancer (the worse-case scenario) by up to a whopping 92 percent. “To catch it early, a woman must get screened annually,” explains Dr. Lela Emad OB/GYN, “This is an important factor for the four out of five women who do not receive routine check-ups that includes a Pap Test.”

What is cervical cancer

At one time, cervical cancer was the most prominent cause of cancer death for American women. But, thanks to early detection and new treatment options developed over the last 40 years, the cervical cancer death rate has been cut in half. The real hero in this story is a simple test most women are very familiar with; the Pap test. This screening procedure makes it possible for healthcare professionals to catch minute changes in the cervix well before it has a chance to develop into cancer. Pap tests can also find cervical cancer early – when it is in its most curable stage – giving women with a positive diagnosis an even better chance of beating the disease.

The latest statistics from the American Cancer Society estimates that in the United States;

  • About 12,820 new cases of invasive cervical cancer will be diagnosed
  • About 4,210 women will die from cervical cancer

What causes cervical cancer?

The vast majority of both women and men will become infected with the Human papillomavirus or HPV at some point during their lifetimes and HPV is found in about 99 percent of cervical cancers cases. Although most HPV infections are benign and disappear on their own, some persist. Of the more than 100 different types of HPV most are considered low-risk and do not lead to cervical cancer. But some high-risk HPV strains persist to cause cervical cell abnormalities and go on to develop into cancer. The two types of the virus HPV-16 and HPV-18 are consider the most high-risk HPV strains.

Who gets cervical cancer

Most cases of cervical cancer are found in women between the ages of 20 and 50, and even women who have entered into menopause may still be at risk. About 20 percent of all cervical cancers are found in women over the age of 65. Cervical cancer rarely occurs in women who have received routine screenings for the disease during the years before they turned 65. In the United States, Hispanic women are most likely to get cervical cancer, followed by African-Americans, American Indians and Alaskan natives, and whites. Asians and Pacific Islanders have the lowest risk of cervical cancer in this country.

What is cervical cancer?

Cancer initiates in the body when otherwise normal cells begin to grow out of control, and it can affect any part of the body and even spread to other areas of the body. Cervical cancer begins in the cells lining the cervix — the lower part of the uterus (womb). Although cervical cancers start from cells in the pre-cancerous stages, only some of the women with pre-cancers of the cervix will go on to actually develop cancer. It normally takes a number of years before cervical pre-cancer turns into full blown cervical cancer, but it can happen in less time in some women. For most women, pre-cancerous cells resolve on their own without any treatment. But, treating all cervical pre-cancers can prevent almost all cervical cancers.

Symptoms of cervical cancer

Symptoms of the more advanced disease have been known to include abnormal or irregular vaginal bleeding, pain during sex, and/or unusual vaginal discharge. Abnormal bleeding symptoms outside of regular menstrual periods, after sexual intercourse or douching and bleeding after a pelvic exam can be symptoms of cervical cancer as can bleeding after menopause. Other symptoms include pelvic pain not related to the menstrual cycle, heavy or unusual discharge, increased urinary frequency and pain during urination. Of course, these symptoms could also be signs of other health problems not related to cervical cancer, but the best way to find out is to talk to a healthcare provider.

Prevention

Precancerous cervical cell changes and early cancers of the cervix generally do not cause any unusual symptoms. For this reason, routine screening through Pap and HPV tests is the best way to catch precancerous cell changes early, thereby preventing the development of cervical cancer.

“Pap test screening is obviously the first line of defense against cervical cancer,” says Dr. Emad. “We recommend Pap tests for women on a semi-annual basis after turning 21.” Regular gynecological Pap tests are the best way to detect most abnormal cell changes due to HPV well before they become cancer.

“Early detection of precancer cells makes it possible for a woman to be effectively treated before it becomes malignant, but unfortunately not every woman in committed to receive a regular Pap Test. This needs to become a priority for every woman, and particularly those who are intent on staying healthy.”

About Women’s OB/GYN Medical Group

Women’s OB/GYN Medical Group offers comprehensive testing with the latest available technology to screen for a full-spectrum of diseases and symptoms, and to monitor conditions as they develop in order to maximize patients’ health and well-being. The Women’s OB/GYN Medical Group strives to better the lives of all women with a holistic approach to women’s health. Visit the website to learn more or call 707-579-1102 to schedule an appointment.