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The facts about licorice extracts for treating menopausal symptoms

Licorice roots have a flavorful history, having been used in ancient Egyptian teas and in traditional Chinese medicines, all the way to today as a flavoring agent and candy. And some women now take licorice extracts as supplements to treat menopausal symptoms. But scientists caution that licorice could pose a health risk by interacting with medications.
Women take licorice extracts as supplements to treat menopausal symptoms. But scientists caution that licorice could pose a health risk by interacting with medications.Licorice roots have a diverse and flavorful history, having been used in ancient Egyptian times as a tea and in traditional Chinese medicines, all the way to today as a flavoring agent and as an ingredient in some licorice candies. Some women now take licorice extracts as supplements to treat hot flashes and other menopausal symptoms. But scientists caution that the substance could pose a health risk by interacting with medications.

The researchers are presenting their results today at the 254th National Meeting & Exposition of the American Chemical Society (ACS).

“Concerns about the risk of stroke and breast cancer associated with conventional hormone therapy are prompting women to seek alternatives,” Richard B. van Breemen, Ph.D., says. “Some take botanical dietary supplements, such as licorice, to treat menopausal symptoms like hot flashes.”

But just because a substance is sold as a supplement in a health food store doesn’t mean it is completely safe for all people to take. And on its own, even as a candy, licorice can be harmful in some cases. The U.S. Food and Drug Administration recommends that licorice not be eaten in large amounts during one sitting, and warns that excessive consumption can lead to irregular heart rhythm and muscle fatigue.

“Consuming too much licorice can be harmful, but in our lab, we wondered whether the small amounts in dietary supplements might also cause problems by interfering with drug metabolism or transportation,” says van Breemen, who is at the University of Illinois at Chicago. “The liver has enzymes that process medications, and if these enzymes are induced or inhibited, the drugs will either be processed too quickly or too slowly, respectively.” He points out that these changes could pose a significant safety risk to those who take a daily licorice dietary supplement along with other medication.

Van Breemen’s team analyzed how three types of licorice — two North American species, Glycyrrhiza uralensis and G. inflata, and a European species called G. glabra — affected liver enzymes involved in drug metabolism. They found that all three species inhibit several of these enzymes. Only G. uralensis and G. inflataextracts were found to induce some of these enzymes. Therefore, the researchers say that G. uralensis and G. inflata are more likely to interfere with drug metabolism when compared to G. glabra.

Consumers would have a difficult time using this information, however, because most supplements don’t list the species on their labels. But the researchers are using this knowledge to develop their own licorice therapy that would be safe and effective for women experiencing menopausal symptoms, such as hot flashes. They plan to start clinical trials on their G. glabra-based supplements next year.


Story Source:

Materials provided by American Chemical Society. Note: Content may be edited for style and length.


Read this article on Science Daily: American Chemical Society. “Licorice is a hot trend in hot flashes, but could interact with medications.” ScienceDaily. ScienceDaily, 21 August 2017. <www.sciencedaily.com/releases/2017/08/170821085705.htm.

Women’s OB/GYN Medical Group Physicians Recognized as Among “Top Doctors” of 2017 by Sonoma County Magazine

Santa Rosa physicians, Lela Emad, Shazah Khawaja, and Susan Logan of NCMA Women’s OB/GYN Medical Group have been chosen as among the top Obstetrics and Gynecology doctors by Sonoma Magazine’s Top Doctors survey.

Santa Rosa physicians, Lela Emad, Shazah Khawaja, and Susan Logan Top Doctors 2017

Amita Kachru, MD, Susan Logan MD, Lela Emad MD, Shazah Khawaja, MD

Sonoma Magazine’s Top Doctor 2017 survey polled Sonoma County doctors and medical specialists for healthcare practitioners they most often recommend to a loved one. More than 300 professionals are noted in the September issue as “the crème de la crème” in more than 50 categories. Among physician peers Dr. Lela Emad, Dr. Shazah Khawaja and Dr. Susan Logan ranked at the top for most likely to be referred in the category of OB/GYN specialists. “For the second year in a row, we are honored to be included among such an elite group of physicians in Sonoma County,” said Dr. Emad. “Our group is devoted to the work we do for women in this community, and it is nice to be recognized by our peers.”

About the Women’s OB/GYN Medical Group

With a team made up of compassionate, expert doctors, midwives, nurses and medical assistants aimed at providing unmatched care to patients, the Women’s OB/GYN Medical Group offers a full range of obstetrics and gynecology services to women in the North Bay region. “By putting our patients first, our goal has always been to meet the healthcare needs of women in a comfortable environment, close to home,” says Dr. Emad. “This is something we’ve been doing for more than 25 years.”

Services offered include:

  • general gynecological health screenings
  • state-of-the-art diagnostics
  • comprehensive pregnancy and postpartum care
  • full mid-wifery services
  • minimally invasive laparoscopic surgery
  • uro-gynecological procedures
  • incontinence care
  • menopause care
  • laser hair reduction, skin care and Botox Cosmetic

Women’s OB/GYN Medical Group’s staff of physicians include; Lela Emad, MD, Shazah Khawaja, MD, Amita Kachru, MD, and Susan Logan, MD along with two new providers; Tara Bartlett, D.O and Melissa A. Seeker, M.D. Together, these doctors share a unique whole-body approach to medicine as they strive to find the underlying causes of a woman’s health problems, rather than simply treating the symptoms. The team of health professionals including Certified Nurse-Midwifes and Nurse Practitioners is committed to both alleviating short-term ailments and maximizing long-term health. The practice partnered with Northern California Medical Associates (NCMA) in 2014 to strengthen its network of experienced healthcare providers, directly benefitting patient access to healthcare specialists in the area.

“The theme of our care is ‘women proudly serving women’,” explains Dr. Emad. “As women we understand the needs and expectations of our patients, and we strive to provide each patient with the best experience possible.”

The Women’s OB/GYN Medical Group works to better the lives of all women with a holistic approach to women’s health. To learn more about these fine physicians and the many services provided by the Women’s OB/GYN Medical Group visit the website. Call for an appointment at (707) 579-1102.

Annual mammograms at 40 prevents the most cancer deaths

 
When to initiate screening for breast cancer, how often to screen, and how long to screen are questions that continue to spark emotional debates.

 

When to initiate screening for breast cancer, how often to screen, and how long to screen are questions that continue to spark emotional debates.When to initiate screening for breast cancer, how often to screen, and how long to screen are questions that continue to spark emotional debates. A new study compares the number of deaths that might be prevented as a result of three of the most widely discussed recommendations for screening mammography. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings may provide valuable guidance to women and their physicians about choosing a screening regimen.

To uncover insights that might help women make informed choices about mammography screening, researchers led by Elizabeth Kagan Arleo, MD, of Weill Cornell Medicine and New York-Presbyterian, and R. Edward Hendrick, PhD, of the University of Colorado School of Medicine, used computer modeling to estimate the possible effects of three schemes: annual screening starting at age 40 years, annual screening at ages 45 to 54 years and then biennial screening at ages 55 to 79 years, and biennial screening at ages 50 to 74 years.

The investigators estimated how many breast cancer deaths might be prevented with the different screening schemes. The team found that the recommendation of annual screening starting at age 40 would result in the greatest reduction in breast cancer-specific deaths: a nearly 40 percent reduction in deaths due to breast cancer, compared with 23 percent to 31 percent reductions with other recommendations.

“Our findings are important and novel because this is the first time the three most widely discussed recommendations for screening mammography have been compared head to head,” said Dr. Arleo. “Our research would be put to good use if, because of our findings, women chose to start annual screening mammography starting at age 40. Over the long term, this would be significant because fewer women would die from breast cancer.”

The researchers’ modeling also considered risks associated with screening, including callbacks for additional imaging and, in some cases, a needle biopsy, both of which may reveal the absence of breast cancer despite a suspicious mammography finding.

“Our results show the differences in the three current recommendations for screening mammography in terms of benefits and risks. Women and their physicians can use these findings to guide choices of when a woman begins screening mammography and how often she gets screened,” said Dr. Hendrick.

An estimated 252,710 new cases of invasive breast cancer and 63,410 new cases of non-invasive breast cancer are expected to be diagnosed in women in the United States in 2017, with 40,610 US women expected to die from breast cancer in 2017. About 33 million screening mammography exams are performed each year.

In an accompanying editorial, Otis Brawley, MD, of the American Cancer Society, noted that it is ultimately an individual’s value judgment as to how many false positive mammograms and biopsies are too many to save one life. He stressed that it is important to acknowledge the limitations of mammography and to make it a priority to develop a better test. “The ideal test would be easy to administer and accurate in women of all ages, meaning there would be few false positives and few tumors would be missed,” he wrote.


Story Source:

Materials provided by Wiley. Note: Content may be edited for style and length.


Journal Reference:

  1. Elizabeth Kagan Arleo, R. Edward Hendrick, Mark A. Helvie, Edward A. Sickles. Comparison of recommendations for screening mammography using CISNET models. Cancer, 2017; DOI: 10.1002/cncr.30842

View this article on ScienceDaily.com; “Comparison of screening recommendations indicates annual mammography: Starting at age 40 prevents the most cancer deaths.” ScienceDaily. ScienceDaily, 21 August 2017.

 

Dr. Tara Bartlett D.O. joins The Women’s OB/GYN Medical Group

Dr. Tara Bartlett, DO joins the Women’s OB/GYN Medical GroupDr. Tara C. Bartlett, DO joins the Women’s OB/GYN Medical Group to become the newest member of a team of healthcare professionals made up of compassionate, expert doctors, midwives, nurses and medical assistants, all aimed at providing unmatched care to patients. Dr. Tara C. Bartlett, D.O., is a practicing obstetrician and gynecologist.  She graduated from University of California, Los Angeles as a Phi Beta Kappa with High Honors.  She holds a B.S. degree in Biology with a minor in Global Studies.  Dr. Bartlett obtained her medical degree at Western University of Health Sciences College of Osteopathic Medicine in California.  She completed her residency at Genesys Regional Medical Center in Grand Blanc, Michigan.

Dr. Bartlett holds numerous awards and certifications including Da Vinci robotic surgery certification.  She is trained in minimally invasive robotic and laparoscopic surgery, hysteroscopic surgery, myosure device, novasure endometrial ablation, nexplanon insertion, and intrauterine device placement.  She has participated in a number of research projects pertaining to her specialty including HPV genotyping research.

Dr.  Bartlett has a special interest in international medicine and was awarded the Rafi Younoszai International/Cross-Cultural Health Scholarship Award in 2013.  She has participated in medical outreach providing OB/GYN services for areas with minimal healthcare access in Peru, the Dominican Republic, and northern Spain.  “We are thrilled to welcome Dr. Bartlett as the newest physician to join our unique group of women healthcare providers,” says Dr. Lela Emad of the Women’s OB/GYN Medical Group. “We are honored to have her in our practice. With this addition, both staff and patients gain a very talented and caring physician focused on providing quality support and unmatched healthcare to patients.”

About the Women’s OB/GYN Medical Group

With a team made up of compassionate, expert doctors, midwives, nurses and medical assistants aimed at providing unmatched care to patients, the Women’s OB/GYN Medical Group offers a full range of obstetrics and gynecology services to women in the North Bay region.  Services offered include;

  • General gynecological health screenings
  • State-of-the-art diagnostics
  • Comprehensive pregnancy and postpartum care
  • Full midwifery services
  • Minimally invasive laparoscopic surgery
  • Uro-gynecological procedures
  • Incontinence care
  • Menopause care
  • Laser hair reduction, skin care and Botox Cosmetic

Along with Dr. Bartlett, the Women’s OB/GYN Medical Group’s staff of physicians includes; Lela Emad, MD, Shazah Khawaja, MD, Amita Kachru, MD, and Susan Logan, MD. Together, these doctors share a unique whole-body approach to medicine as they strive to find the underlying causes of a woman’s health problems, rather than simply treating the symptoms. Every one of the health professionals at Women’s OB/GYN is committed to both alleviating short-term ailments and maximizing long-term health.

The Women’s OB/GYN Medical Group strives to better the lives of all women with a holistic approach to women’s health. To learn more about these fine physicians and the many services provided by the Women’s OB/GYN Medical Group visit the website. Call for an appointment at (707) 579-1102.

New Study Concludes: Women have more active brains than men

Largest functional brain imaging study to date identifies specific brain differences between women and men, according to a new report in the Journal of Alzheimer’s Disease

 In the largest functional brain imaging study to date, researchers compared 46,034 brain SPECT (single photon emission computed tomography) imaging studies provided by nine clinics, quantifying differences between the brains of men and women.

The study findings explain why women tend to exhibit greater strengths in the areas of empathy, intuition, collaboration, self-control, and concern.
Side view of the brain summarizing blood flow results from tens of thousands of study subjects shows increased blood flow in women compared to men, highlighted in the red colored areas of the brain: the cingulate gyrus and precuneus. Men in this image have higher blood flow in blue colored areas — the cerebellum.
Credit: Journal of Alzheimer’s Disease

The study findings of increased prefrontal cortex blood flow in women compared to men may explain why women tend to exhibit greater strengths in the areas of empathy, intuition, collaboration, self-control, and appropriate concern. The study also found increased blood flow in limbic areas of the brains of women, which may also partially explain why women are more vulnerable to anxiety, depression, insomnia, and eating disorders.

In the largest functional brain imaging study to date, the Amen Clinics (Newport Beach, CA) compared 46,034 brain SPECT (single photon emission computed tomography) imaging studies provided by nine clinics, quantifying differences between the brains of men and women. The study is published in the Journal of Alzheimer’s Disease.

Lead author, psychiatrist Daniel G. Amen, MD, founder of Amen Clinics, Inc., commented, “This is a very important study to help understand gender-based brain differences. The quantifiable differences we identified between men and women are important for understanding gender-based risk for brain disorders such as Alzheimer’s disease. Using functional neuroimaging tools, such as SPECT, are essential to developing precision medicine brain treatments in the future.”

The brains of women in the study were significantly more active in many more areas of the brain than men, especially in the prefrontal cortex, involved with focus and impulse control, and the limbic or emotional areas of the brain, involved with mood and anxiety. The visual and coordination centers of the brain were more active in men. SPECT can measure blood perfusion in the brain. Images acquired from subjects at rest or while performing various cognitive tasks will show different blood flow in specific brain regions.

Subjects included 119 healthy volunteers and 26,683 patients with a variety of psychiatric conditions such as brain trauma, bipolar disorders, mood disorders, schizophrenia/psychotic disorders, and attention deficit hyperactivity disorder (ADHD). A total of 128 brain regions were analyzed for subjects at baseline and while performing a concentration task.

Understanding these differences is important because brain disorders affect men and women differently. Women have significantly higher rates of Alzheimer’s disease, depression, which is itself is a risk factor for Alzheimer’s disease, and anxiety disorders, while men have higher rates of (ADHD), conduct-related problems, and incarceration (by 1,400%).

Editor-in-Chief of the Journal of Alzheimer’s Disease and Dean of the College of Sciences at The University of Texas at San Antonio, Dr. George Perry said, “Precisely defining the physiological and structural basis of gender differences in brain function will illuminate Alzheimer’s disease and understanding our partners.”

Story Source: Materials provided by IOS Press. Note: Content may be edited for style and length.


Journal Reference:

  1. Daniel G. Amen, Manuel Trujillo, David Keator, Derek V. Taylor, Kristen Willeumier, Somayeh Meysami, Cyrus A. Raji. Gender-Based Cerebral Perfusion Differences in 46,034 Functional Neuroimaging Scans. Journal of Alzheimer’s Disease, 2017; 1 DOI: 10.3233/JAD-170432

Read this article on Science Daily: IOS Press. “Women have more active brains than men: Largest functional brain imaging study to date identifies specific brain differences between women and men, according to a new report in the Journal of Alzheimer’s Disease.” ScienceDaily. ScienceDaily, 7 August 2017.


The Women’s OB/GYN Medical Group strives to better the lives of all women with a holistic approach to women’s health. Call for an appointment today: (707) 579-1102. Visit our website: www.womensobgynmed.com#womenhearthealth

BMI determines risk of heart disease in middle-aged women

A woman’s race and where on her body she packs on pounds at midlife could give her doctor valuable clues to her likelihood of having greater volumes of heart fat, a potential risk factor for heart disease, according to new research.

BMI determines risk of heart disease in middle-aged women

A woman’s race and where on her body she packs on pounds at midlife could give her doctor valuable clues to her likelihood of having greater volumes of heart fat, a potential risk factor for heart disease, according to new research led by the University of Pittsburgh Graduate School of Public Health.

The findings, published online today in the journal Menopause, show that black women who put on fat around their midsection during midlife are more likely to accumulate fat around their hearts, whereas white women’s risk of fatty hearts is higher when they add weight all over. The results echo the findings of a Pitt Public Health study three years ago in men.

BMI determines risk of heart disease in middle-aged women

“Excess fat around the heart, in both men and women, is an evolving risk factor for heart disease. But how can clinicians see it at a regular physical? They can’t without a special heart scan,” said senior author Samar El Khoudary, Ph.D., M.P.H., associate professor of epidemiology at Pitt Public Health. “This study, coupled with our previous study in men, gives doctors another tool to evaluate their patients and get a better sense of their heart disease risk. It also may lead to suggestions for lifestyle modifications to help patients lessen that risk.”

El Khoudary and her team evaluated clinical data, such as CT scans and blood pressure, on 524 women from Pittsburgh and Chicago enrolled in the Study of Women’s Health Across the Nation (SWAN). The women were in varying stages of menopause, averaged 51 years old and were not on hormone replacement therapy.

The bottom line on BMI and heart disease

After accounting for the potential health effects of lifestyle and socioeconomic factors, such as smoking, alcohol consumption and financial strain, the researchers determined that, not surprisingly, the more fat a women carries overall, the higher her risk for a fatty heart.

However, white women with higher body mass indexes, or BMI, which is a measure of overall body fat, had significantly more heart fat, as measured by a CT scan, than black women with the same BMI. BMI determines risk of heart disease in middle-aged women

For black women, the levels of heart fat were greater if they carried more fat in their midsection, as measured by a cross-sectional CT scan, compared with white women with the same volume of fat in their midsection.

El Khoudary’s team found that the heart fat black women with larger waistlines accumulate is closer to their hearts than the fat the white women with higher BMI’s accumulate. Fat close to the heart secretes inflammatory markers directly to the heart tissue and produces a greater detrimental effect as it expands.

“We’ve now come to very similar conclusions that show excess abdominal fat is worse for both black men and women, and a higher BMI is worse for white men and women when it comes to their odds of having more fat around their hearts,” said El Khoudary, who noted that the current analysis could not assess changes over time. “There is something going on here that warrants further investigation to determine why it is happening and what tailored interventions doctors may prescribe to help their patients lower their risk.”


Story Source: Materials provided by University of Pittsburgh Schools of the Health Sciences. Note: Content may be edited for style and length.

Read this article on ScienceDaily: University of Pittsburgh Schools of the Health Sciences. “Risk of a fatty heart linked to race, type of weight gain in middle-aged women.” ScienceDaily. ScienceDaily, 2 August 2017.


The Women’s OB/GYN Medical Group strives to better the lives of all women with a holistic approach to women’s health. Call for an appointment today: (707) 579-1102. Visit our website: www.womensobgynmed.com

Malaria drug may prevent Zika virus from infecting fetus

Studying pregnant mice, researchers at Washington University School of Medicine in St. Louis found that Zika virus manipulates the body's normal barrier to infection, and that hydroxychloroquine, a malaria drug related to chloroquine, interferes with this process, protecting the fetus from viral infection.Zika virus infects the fetus by manipulating the body’s normal barrier to infection, according to a new study of pregnant mice. Moreover, the study showed that a drug that interferes with this process protects the fetus from viral infection. That drug is already approved for use in pregnant women for other medical purposes.
Devastating consequences of Zika virus infection are suffered in the womb, where the virus can cause brain damage and sometimes death.

Studying pregnant mice, researchers at Washington University School of Medicine in St. Louis have learned that the Zika virus infects the fetus by manipulating the body’s normal barrier to infection. Moreover, they showed that a malaria drug that interferes with this process protects the fetus from viral infection. That drug already is approved for use in pregnant women for other medical purposes.

“We found that the malaria drug hydroxychloroquine effectively blocks viral transmission to the fetus,” said senior author Indira Mysorekar, PhD, an associate professor of obstetrics and gynecology, and of pathology and immunology. “This drug already is used in pregnant women to treat malaria, and we suggest that it warrants evaluation in primates and women to diminish the risks of Zika infection and disease in developing fetuses.”

The findings are published July 10 in The Journal of Experimental Medicine.

In late 2015, doctors in Brazil began to notice a surge in the number of babies born with microcephaly, or unusually small heads, an indicator of neurological damage. The epidemic soon was linked to the mosquito-borne Zika virus, which was spreading through the tropical parts of the Americas. Doctors advised pregnant women to avoid mosquito bites by wearing bug spray and long-sleeved clothing, but had little other advice to offer. There were, and still are, no drugs or vaccines approved for use in pregnant women to protect them or their fetuses from Zika infection.

The developing fetus is uniquely vulnerable to damage from infection, so the body mobilizes robust defenses to keep microbes from ever reaching the fetus in the first place. The placenta is the last line of defense. Mysorekar and others have shown that a process known as autophagy — the cellular waste-disposal pathway by which cells grind up debris, unwanted organelles and invading microbes — is an important part of the formidable placental barrier to infection. However, previous studies by Mysorekar and others have shown that Zika not only can invade the placenta, but multiply there.

To learn more about how Zika breaches the placenta, Mysorekar, postdoctoral fellow Bin Cao, PhD, and colleagues infected human placental cells with Zika virus. They found that exposure to the virus activated genes related to autophagy.

However, when the researchers treated the cells with drugs to ramp up the autophagy pathway, the number of cells infected with Zika virus increased. Drugs that suppressed autophagy resulted in fewer placental cells infected with Zika virus. In other words, the virus multiplied and spread more effectively when the researchers dialed up the barrier response, and performed more sluggishly when they dialed it down. The virus seemed to be doing a form of microbial martial arts, turning the body’s weapons to its own advantage.

Mysorekar and colleagues verified these findings using mice whose autophagy response was hobbled by low levels of a key autophagy protein. They infected two groups of pregnant mice with Zika: one in which the autophagy process was disrupted and the other in which it worked normally.

Five days after infection, the mothers with a weak autophagy response had about the same amount of virus in their bloodstreams as the mice with a normal response. However, in mice with a weak autophagy response, the researchers found 10 times fewer viruses in the placenta and the heads of the fetuses and less damage to the placentas.

“It appears that Zika virus takes advantage of the autophagy process in the placenta to promote its survival and infection of placental cells,” Cao said.

Since hydroxychloroquine suppresses the autophagy response, the researchers questioned whether it also could protect fetuses against Zika.

To find out, they repeated the mouse experiment using only mice with a normal autophagy response. Female mice at day nine of pregnancy were infected with Zika and then dosed with hydroxychloroquine or placebo every day for the next five days.

Following treatment, the researchers found significantly less virus in the fetuses and placentas from the mice that had received hydroxychloroquine. In addition, these placentas showed less damage and the fetuses regained normal growth. Both the untreated and the treated mothers had about the same amount of Zika virus in their bloodstreams, indicating that hydroxychloroquine was able to protect fetuses even when the virus was circulating through the mother.

Although hydroxychloroquine has been used safely in pregnant women for short periods of time, the researchers caution that further studies are needed before it can be used in pregnant women to fend off Zika. Pregnant women living in areas where Zika circulates may need to take the drug for the duration of their pregnancies, and the safety of hydroxychloroquine for long-term use is unknown.

“We would urge caution but nevertheless feel our study provides new avenues for feasible therapeutic interventions,” said Mysorekar, who is also co-director of the university’s Center for Reproductive Health Sciences. “Our study suggests that an autophagy-based therapeutic intervention against Zika may be warranted in pregnant women infected with Zika virus.”

The Women’s OB/GYN Medical Group strives to better the lives of all women with a holistic approach to women’s health. Call for an appointment today: (707) 579-1102. Visit our website: www.womensobgynmed.com


Story Source:

Materials provided by Washington University School of Medicine. Original written by Tamara Bhandari. Note: Content may be edited for style and length.


Journal Reference:

  1. Indira Mysorekar et al. Inhibition of autophagy limits vertical transmission of Zika virus in pregnant mice. The Journal of Experimental Medicine, July 2017 DOI: 10.1084/jem.20170957

Read this article on ScienceDaily: Washington University School of Medicine. “Malaria drug protects fetuses from Zika infection: Treatment prevents virus from crossing placenta to infect fetus, mouse study shows.” ScienceDaily. ScienceDaily, 10 July 2017. www.sciencedaily.com/releases/2017/07/170710091702.htm.

Diet that includes vegetable protein may protect against early menopause

Eating more vegetable protein may protect against early menopause: Study shows modest but significant lower risk in older women, linking diet menopause.Results of a new study from epidemiologists at the University of Massachusetts Amherst and Harvard T.H. Chan School of Public Health suggest that long-term diet that includes a high intake of vegetable protein from such foods as whole grains, soy and tofu, may protect women from early menopause and could prolong reproductive function. Diet menopause.

Consuming enriched pasta, dark bread and cold cereal were especially associated with lower risk, while they observed no similar relation to eating animal sources of protein.

“A better understanding of how dietary vegetable protein intake is associated with ovarian aging may identify ways for women to modify their risk of early onset menopause and associated health conditions,” write first author and then-graduate student Maegan Boutot, with her advisor, professor Elizabeth Bertone-Johnson. Details appear in the current early online edition of the American Journal of Epidemiology.

Early menopause, the cessation of ovarian function before age 45, affects about 10 percent of women and is associated with higher risk of cardiovascular disease, osteoporosis and early cognitive decline, the authors note. Few studies have evaluated how protein intake is associated with menopause timing, they add, and to their knowledge this is the first to look specifically at early menopause.

Boutot, Bertone-Johnson and colleagues in the School of Public Health and Health Sciences at UMass Amherst, with others, evaluated the relationship between diet and risk of early menopause among members of the Nurses’ Health Study II (NHS2), an ongoing prospective study of 116,000 women aged 25-42 when they entered it in 1989.

Participants were asked to report how often they ate a single serving of 131 foods, beverages and supplements over the previous year, from “never or less than once a month” to “6+ per day.” They observed that women consuming approximately 6.5 percent of their daily calories as vegetable protein had a significant 16 percent lower risk of early menopause compared to women whose intake was approximately 4 percent of calories.

Diet Menopause

For a woman with a 2,000 calorie per day diet, the authors explain, this is equal to three to four servings of such foods as enriched pasta, breakfast cereal, tofu and nuts, or about 32.5 grams a day. They adjusted for age, smoking, body mass index and other possible confounding factors.

Boutot and Bertone-Johnson add, “Though relatively few women in our study consumed very high levels of vegetable protein and our power for analyses of more extreme intake levels was limited, women consuming 9 or more percent of their calories from vegetable protein had a hazard ratio of 0.41 (95 percent confidence interval = 0.19-0.88)” compared to those eating less than 4 percent.

Others on the study team were from Brigham and Women’s Hospital and Harvard Medical School. The study was supported by a grant from NIH’s Eunice Kennedy Shriver National Institute of Child Health and Human Development.

For the NHS2, follow-up questionnaires have assessed nurses’ lifestyle behaviors and medical conditions every two years. Nearly 90 percent have continued to participate in followup. Diet was assessed five times over the 20-year study, allowing the researchers to capture within-person variation in changes in food and nutrient intake over times, Boutot explains. Participants in the study contributed more than 1 million person-years of follow-up, during which 2,041 women experienced early menopause.

Boutot and Bertone-Johnson suggest that more prospective studies of their findings are warranted, including studies that compare soy-based and non-soy vegetable proteins.

Story Source:

Materials provided by University of Massachusetts at Amherst. Note: Content may be edited for style and length. University of Massachusetts at Amherst. “Eating more vegetable protein may protect against early menopause: Study shows modest but significant lower risk.” Read this article on ScienceDaily:  ScienceDaily, 26 June 2017. www.sciencedaily.com/releases/2017/06/170626093604.htm.


The Women’s OB/GYN Medical Group strives to better the lives of all women with a holistic approach to women’s health. Call for an appointment today: (707) 579-1102. Visit our website: www.womensobgynmed.com

Menstrual cycle has no impact on how a woman’s brain functions

Levels of estrogen, progesterone and testosterone in one's system have no impact on the working memory, cognitive bias or ability to pay attention to two things at once.A new study published in Frontiers in Behavioral Neuroscience is setting out to change the way we think about the menstrual cycle. While it’s often been assumed that anyone who’s menstruating isn’t working at top mental pitch, Professor Brigitte Leeners and her team of researchers have found evidence to suggest that that’s not the case. They examined three aspects of cognition across two menstrual cycles, and found that the levels of estrogen, progesterone and testosterone in your system have no impact on your working memory, cognitive bias or ability to pay attention to two things at once. While some hormones were associated with changes across one cycle in some of the women taking part, these effects didn’t repeat in the following cycle. Overall, none of the hormones the team studied had any replicable, consistent effect on study participants’ cognition.

Professor Leeners, team lead, said: “As a specialist in reproductive medicine and a psychotherapist, I deal with many women who have the impression that the menstrual cycle influences their well-being and cognitive performance.” Wondering if this anecdotal evidence could be scientifically proven — and questioning the methodology of many existing studies on the subject — the team set out to shed some light on this controversial topic.

The study published today uses a much larger sample than usual, and (unlike most similar studies) follows women across two consecutive menstrual cycles. The team, working from the Medical School Hannover and University Hospital Zürich, recruited 68 women to undergo detailed monitoring to investigate changes in three selected cognitive processes at different stages in the menstrual cycle. While analysis of the results from the first cycle suggested that cognitive bias and attention were affected, these results weren’t replicated in the second cycle. The team looked for differences in performance between individuals and changes in individuals’ performance over time, and found none.

Professor Leeners said, “The hormonal changes related to the menstrual cycle do not show any association with cognitive performance. Although there might be individual exceptions, women’s cognitive performance is in general not disturbed by hormonal changes occurring with the menstrual cycle.”

Professor Leeners cautions, however, that there’s more work to do. While this study represents a meaningful step forward, larger samples, bigger subsamples of women with hormone disorders, and further cognitive tests would provide a fuller picture of the way that the menstrual cycle affects the brain. In the meantime, Professor Leeners hopes her team’s work will start the long process of changing minds about menstruation.


Story Source:

Materials provided by Frontiers. Note: Content may be edited for style and length.


Journal Reference:

  1. Brigitte Leeners, Tillmann H. C. Kruger, Kirsten Geraedts, Enrico Tronci, Toni Mancini, Fabian Ille, Marcel Egli, Susanna Röblitz, Lanja Saleh, Katharina Spanaus, Cordula Schippert, Yuangyuang Zhang, Michael P. Hengartner. Lack of Associations between Female Hormone Levels and Visuospatial Working Memory, Divided Attention and Cognitive Bias across Two Consecutive Menstrual Cycles. Frontiers in Behavioral Neuroscience, 2017; 11 DOI: 10.3389/fnbeh.2017.00120

See this article on science daily:  Frontiers. “Menstruation doesn’t change how your brain works — period: Normonal changes during the menstrual cycle have no impact on aspects of cognition, study shows.” ScienceDaily. ScienceDaily, 4 July 2017. www.sciencedaily.com/releases/2017/07/170704093610.htm.

How to always look good at the beach with Laser Hair Removal

With the arrival of summer Dr. Lela Emad of Women’s OB/GYN Medical Group discusses the advantages offered by laser hair removal.

With a heatwave bearing down on Northern California pushing temperatures to the maximum, many people are heading to the beach or hanging out at the pool. Being swimsuit ready is easy with laser hair removal.

The process of summer waxing and constantly shaving unwanted hair, then repeat – and repeat again can be a burdensome routine when all you want to do is get out, dive in and cool off. There is a way to be swimsuit ready all summer long with laser hair removal.  “Traditional methods for removing hair like shaving, tweezing and waxing can be very cumbersome and time consuming for women,” explains Dr. Lela Emad of Women’s OB/GYN Medical Group in Santa Rosa. “Laser hair reduction offers a safe and very effective medical procedure to permanently terminate hair growth from unwanted areas.”

What is Laser Hair Reduction?

Laser hair removal is actually a medical procedure that employs an intense, pulsating beam of light to remove unwanted hair. A focused laser beam passes through the skin to penetrate and essentially vaporize individual hair follicles. The intense heat of the laser damages the hair follicle without harming surrounding skin and tissue. This process acts to inhibit future hair growth and although it may not completely guarantee permanent hair removal, over the course of a few treatments, it can provide an extended hair-free period. Periodic follow-up maintenance treatments are recommended as well.

The procedure is extremely precise and takes only a few minutes to remove hair from small areas, such as the upper lip or chin, and about an hour to treat larger areas, such as the back or legs. Laser hair reduction may require up to five sessions for optimal outcomes, and when performed properly, the procedure successfully terminates hair growth from treated areas in the vast majority of (up to 90%) of women.

Does it work for everyone?

Although anyone can undergo laser hair removal, best results depend on a person’s hair color and skin type. For example, people who have light skin and dark hair have the best results overall due to how the laser beam targets the pigment (melanin) in the hair. Advances in technology over recent years have made laser hair removal an option even for people who have darker skin.

Laser hair removal isn’t always as effective for hair colors such as white, gray, blond or even red because it’s more difficult for the laser to target that range of color,” said Dr. Emad. “Although people with lighter color hair will see results, it may not be as obvious as those with darker hair color.”

While laser hair reduction is fast and easy for patients, it is still a medical procedure that requires an experienced technician to ensure it is performed safely and effectively. The physicians at Women’s OB/GYN Medical Group carry years of experience in performing laser hair reduction and they take care to attend to any discomfort or bad reactions patients may have to the procedure.

Best outcomes for laser hair removal

Laser hair removal leaves skin smooth and soft on the underarms, legs and arms, hands, back, face, bikini area. The results are always immediate and quite lasting. And since hair follicles are essentially transformed by laser light, hair typically will not grow back as quickly as prior to the treatment and occasional touch-ups are recommended to keep the skin smooth and hair-free.

“Patients who have experienced laser technology for hair removal tend to feel better about the look of their skin, and many report experiencing an improvement in body image that gives a boost of confidence,” says Dr. Email. “Above all else, patients appreciate the convenience it provides to the grooming routine.”

About Women’s OB/GYN Laser Hair Removal

Women’s OB/GYN physicians also offer expert advice and products for general skin care and treatment. Call (707) 579-1102 to schedule an appointment and for more information about laser hair reduction and skin care offered by the group. Visit the website to learn more.